RESOURCE: ATSDR Toxicological Profiles (external link)

Information About Contaminants Found at Hazardous Waste Sites. These are available here (external link to ...



By Congressional mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles are developed from a priority list of 275 substances. ATSDR also prepares toxicological profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on substances related to federal sites.

So far, 308 toxicological profiles have been published or are under development as "finals" or "drafts for public comment"; 289 profiles were published as finals; 132 profiles have been updated. Currently, 11 profiles are being revised based on public comments received; 1 profile is under development; 1 profile is in public comment. These profiles cover more than 250 substances.

Toxicological profiles are developed in two stages:

(1) DRAFTS: The toxicological profiles are first produced as drafts. ATSDR announces in the Federal Register the release of these draft profiles for a 90 day public comment period. Request draft toxicological profiles from ATSDR's Division of Toxicology and Environmental Medicine.

(2) FINALS: After the 90 day comment period, ATSDR considers incorporating all comments into the documents. ATSDR finalizes the profiles and the National Technical Information Service (NTIS) distributes them.